MCQOPTIONS
Saved Bookmarks
MCQOPTIONS
This section includes 19 Mcqs, each offering curated multiple-choice questions to sharpen your Genetic Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Introduction into host organism can also be done by using a DNA construct, which when transcribed, generates an RNA which is _________ |
| A. | circular |
| B. | linear |
| C. | double stranded |
| D. | self-complementary |
| Answer» E. | |
| 2. |
siRNAs can either be introduced directly or by microinjection. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
DNA _________ is also a method for gene silencing through short RNAs. |
| A. | acetylation |
| B. | phosphorylation |
| C. | methylation |
| D. | acylation |
| Answer» D. acylation | |
| 4. |
The process of RNA inactivation by siRNAs is termed as ___________ |
| A. | RNA silencing |
| B. | RNA interference |
| C. | Short RNA inactivation |
| D. | RNA disfunction |
| Answer» C. Short RNA inactivation | |
| 5. |
Double stranded RNA is cleaved by a nuclease called as Dicer and small fragments are generated known as ___________ |
| A. | short interfering RNAs |
| B. | long interfering RNAs |
| C. | short interspersed RNAs |
| D. | long interspersed RNAs |
| Answer» B. long interfering RNAs | |
| 6. |
In some organisms, presence of double stranded RNAs leads to breakdown of corresponding single stranded mRNA. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 7. |
Down regulation of expression of endogenous genes by transformation with constructs that would generate sense RNA, rather than anti-sense RNA is known as ___________ |
| A. | suppression |
| B. | co-suppression |
| C. | multisuppression |
| D. | anti-suppression |
| Answer» C. multisuppression | |
| 8. |
The method of post transcriptional gene silencing is particularly useful in ___________ |
| A. | plants |
| B. | animals |
| C. | insects |
| D. | microorganisms |
| Answer» B. animals | |
| 9. |
If methods are based on cellular processes that lead to inactivation of gene expression by affecting the RNA, then it is called as ___________ |
| A. | transcriptional |
| B. | pre-transcriptional |
| C. | post-transcriptional |
| D. | translational |
| Answer» D. translational | |
| 10. |
SIRNAS_CAN_EITHER_BE_INTRODUCED_DIRECTLY_OR_BY_MICROINJECTION._IS_THE_GIVEN_STATEMENT_TRUE_OR_FALSE??$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 11. |
Introduction_into_host_organism_can_also_be_done_by_using_a_DNA_construct,_which_when_transcribed,_generates_a_RNA_which_is__________$ |
| A. | circular |
| B. | linear |
| C. | double stranded |
| D. | self-complementary |
| Answer» E. | |
| 12. |
DNA _________ is also a method for gene silencing through short RNAs? |
| A. | acetylation |
| B. | phosphorylation |
| C. | methylation |
| D. | acylation |
| Answer» D. acylation | |
| 13. |
The process of RNA inactivation by siRNAs is termed as: |
| A. | RNA silencing |
| B. | RNA interference |
| C. | Short RNA inactivation |
| D. | RNA disfunction |
| Answer» C. Short RNA inactivation | |
| 14. |
Double stranded RNA is cleaved by a nuclease called as Dicer and small fragments are generated known as: |
| A. | short interfering RNAs |
| B. | long interfering RNAs |
| C. | short interspersed RNAs |
| D. | long interspersed RNAs |
| Answer» B. long interfering RNAs | |
| 15. |
In some organisms, presence of double stranded RNAs leads to breakdown of corresponding single stranded mRNA. Is the given statement true or false? |
| A. | True |
| B. | False |
| Answer» B. False | |
| 16. |
Down regulation of expression of endogenous genes by transformation with constructs that would generate sense RNA, rather than anti-sense RNA is known as: |
| A. | suppression |
| B. | co-suppression |
| C. | multisuppression |
| D. | anti-suppression |
| Answer» C. multisuppression | |
| 17. |
The method of post transcriptional gene silencing is particularly useful in: |
| A. | plants |
| B. | animals |
| C. | insects |
| D. | microorganisms |
| Answer» B. animals | |
| 18. |
Choose the incorrect statement for the method based on antisense RNA. |
| A. | RNA is synthesized complementary to the sequence of the gene which is to be inactivated |
| B. | It is achieved by placing a DNA sequence which encodes RNA complementary to the RNA to be inactivated |
| C. | Expression of the endogenous gene is diminished |
| D. | This method is preferred over gene disruption has gene inactivation can be achieved completely |
| Answer» E. | |
| 19. |
If methods are based on cellular processes that lead to inactivation of gene expression by affecting the RNA, then it is called as: |
| A. | transcriptional |
| B. | pre-transcriptional |
| C. | post-transcriptional |
| D. | translational |
| Answer» D. translational | |