MCQOPTIONS
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MCQOPTIONS
This section includes 21 Mcqs, each offering curated multiple-choice questions to sharpen your Biotechnology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
T cells are important in controlling |
| A. | virus infections |
| B. | allergy |
| C. | autoimmunity |
| D. | all of these |
| Answer» E. | |
| 2. |
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with |
| A. | Ig MAbs |
| B. | IgG |
| C. | IgA |
| D. | IgE |
| Answer» B. IgG | |
| 3. |
The antigen-specific lymphocytes can be immortalized by which of the following method? |
| A. | Transfection with tumor derived DNA |
| B. | Hybridization with a suitable lymphoid tumor cell |
| C. | Transformation following infection by Epstein-Barr virus (EB V) |
| D. | All of the above |
| Answer» E. | |
| 4. |
Which type of cell actually secrets antibodies? |
| A. | plasma cells |
| B. | T cells |
| C. | macrophages |
| D. | dendritic cells |
| Answer» B. T cells | |
| 5. |
Helper T cells assist in the functions of |
| A. | certain B cells |
| B. | certain T cells |
| C. | certain B cells and other T cells |
| D. | none of the above |
| Answer» D. none of the above | |
| 6. |
The EBV-hybridoma technique |
| A. | immortalizes the donor Bcells |
| B. | facilitates the proliferation of antigen specific B cells |
| C. | gives much higher hybridization frequencies |
| D. | all of the above |
| Answer» E. | |
| 7. |
In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc., |
| A. | T8 cells are greatly reduced |
| B. | T8 cells are greatly increased |
| C. | T4 cells are greatly reduced |
| D. | T4 cells are greatly increased |
| Answer» B. T8 cells are greatly increased | |
| 8. |
In human B cells and T cells are matured in the |
| A. | bone marrow and thymus respectively |
| B. | lymph nodes and spleen respectively |
| C. | bursa and thymus respectively |
| D. | none of these |
| Answer» B. lymph nodes and spleen respectively | |
| 9. |
T cells are the source of |
| A. | interleukin |
| B. | interferon |
| C. | lymphotoxin |
| D. | all of these |
| Answer» E. | |
| 10. |
The primary B cell receptor is |
| A. | IgD |
| B. | IgG |
| C. | IgA |
| D. | IgE |
| Answer» B. IgG | |
| 11. |
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at |
| A. | high frequencies |
| B. | moderate frequencies |
| C. | low frequencies |
| D. | at no frequency |
| Answer» B. moderate frequencies | |
| 12. |
The hybrid cells can be propagated |
| A. | in tissue culture |
| B. | as ascites in peritoneal cavity of mice |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 13. |
TC cells are important in controlling |
| A. | virus infections |
| B. | allergy |
| C. | autoimmunity |
| D. | all of these |
| Answer» E. | |
| 14. |
The cross linkage of antigens by antibodies is known as |
| A. | agglutination |
| B. | complement fixation |
| C. | a cross reaction |
| D. | all of these |
| Answer» B. complement fixation | |
| 15. |
In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a |
| A. | hybridoma |
| B. | myeloma |
| C. | natural killer cell |
| D. | lymphoblast |
| Answer» B. myeloma | |
| 16. |
The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as |
| A. | transformation of antigen specific B lymphocytes (EBV) |
| B. | hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes |
| C. | combination of EB Vand hybridoma techniques |
| D. | all of these |
| Answer» E. | |
| 17. |
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the |
| A. | absence of human immune response against murine proteins (HAMA) response |
| B. | presence of HAMA response |
| C. | poor recognition of immunoglobulin, Ig constant regions |
| D. | all of the above |
| Answer» B. presence of HAMA response | |
| 18. |
An example of mosaic antigen is |
| A. | virus |
| B. | bacteria |
| C. | a hapten |
| D. | protein |
| Answer» B. bacteria | |
| 19. |
Small simple molecules are |
| A. | poor antigens |
| B. | rich antigens |
| C. | moderate antigens |
| D. | heterophilic antigens |
| Answer» B. rich antigens | |
| 20. |
A cytokine that stimulates the activity of B and T cells is |
| A. | lymphotoxin |
| B. | interlukin-2 |
| C. | interlukin-1 |
| D. | all of these |
| Answer» C. interlukin-1 | |
| 21. |
Which of the following is correct? |
| A. | rabbits do not make myelomas whereas mice are unable to synthesize antibodies |
| B. | rabbits do not make myelomas whereas mice are able to synthesize antibodies |
| C. | rabbits make myelomas whereas mice are unable to synthesize antibodies |
| D. | rabbits make myelomas whereas mice are able to synthesize antibodies |
| Answer» B. rabbits do not make myelomas whereas mice are able to synthesize antibodies | |