MCQOPTIONS
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MCQOPTIONS
This section includes 20 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
If the Mut H cuts the DNA at the 5’ side of the mismatch then which nuclease is activated? |
| A. | Exonuclease VII |
| B. | Exonuclease VIII |
| C. | Exonuclease I |
| D. | Exonuclease IX |
| Answer» B. Exonuclease VIII | |
| 2. |
By which enzyme does E. coli tags its parental DNA strand? |
| A. | Methylase |
| B. | Polymerase |
| C. | Phosphorylase |
| D. | Acetylase |
| Answer» B. Polymerase | |
| 3. |
Mismatch repair system is ATP dependent. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 4. |
The nicking of DNA is followed by the adherence of a helicase known as __________ |
| A. | Uvr D |
| B. | Uvr A |
| C. | Uvr B |
| D. | Uvr C |
| Answer» B. Uvr A | |
| 5. |
Mut S recruits how many component(s) to the mismatched site? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 6. |
MUT_S_RECRUITS_HOW_MANY_COMPONENT(S)_TO_THE_MISMATCHED_SITE??$ |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 7. |
Mismatch repair system is ATP dependent.$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 8. |
The_nicking_of_DNA_is_followed_by_the_adherence_of_a_helicase_known_as___________$ |
| A. | Uvr D |
| B. | Uvr A |
| C. | Uvr B |
| D. | Uvr C |
| Answer» B. Uvr A | |
| 9. |
High level of mutation in the germ cells is acceptable but in somatic cells can be catastrophic. |
| A. | True |
| B. | False |
| Answer» C. | |
| 10. |
What are the eukaryotic components of Mut S and Mut L of E. coli? |
| A. | MSH, MLH |
| B. | MHS, MHL |
| C. | MLS, PMS |
| D. | PMS, MHL |
| Answer» B. MHS, MHL | |
| 11. |
If the Mut H cuts the DNA at the 5’ side of the mismatch then which nuclease is activated?$ |
| A. | Exonuclease VII |
| B. | Exonuclease VIII |
| C. | Exonuclease I |
| D. | Exonuclease IX |
| Answer» B. Exonuclease VIII | |
| 12. |
By_which_enzyme_does_E._coli_tags_its_parental_DNA_strand? |
| A. | Methylase |
| B. | Polymerase |
| C. | Phosphorylase |
| D. | Acetylase |
| Answer» B. Polymerase | |
| 13. |
In E. coli mismatches are detected by which repair protein? |
| A. | Mut H |
| B. | Mut L |
| C. | Mut S |
| D. | Mut D |
| Answer» D. Mut D | |
| 14. |
How many steps are required to attain mismatch repair? |
| A. | 1 |
| B. | 3 |
| C. | 2 |
| D. | 4 |
| Answer» D. 4 | |
| 15. |
Detection of mismatches and fidelity of replication is maintained by mutation repair system. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 16. |
By which process miss-incorporated base can change into a permanent mutation? |
| A. | Replication |
| B. | Transcription |
| C. | Translation |
| D. | Transposition |
| Answer» B. Transcription | |
| 17. |
What is the dinucleotide sequence of microsatellites? |
| A. | CA |
| B. | AT |
| C. | CC |
| D. | GC |
| Answer» B. AT | |
| 18. |
The mutation occurs at a random basis within a genome. |
| A. | True |
| B. | False |
| Answer» C. | |
| 19. |
What is the overall rate at which new mutations arise spontaneously at any given site on the chromosome per round of replication? |
| A. | ≈ 10-8 – 10-12 |
| B. | ≈ 10-7 – 10-9 |
| C. | ≈ 10-6 – 10-11 |
| D. | ≈ 10-5 – 10-10 |
| Answer» D. ‚Äö√Ñ√∂‚àö¬¢‚àö‚Ć 10-5 ‚Äö√Ñ√∂‚àö√ë‚àö¬® 10-10 | |
| 20. |
How many kinds of mutation are found in DNA which includes mutation of only one base? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |