MCQOPTIONS
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MCQOPTIONS
This section includes 64 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The most popular indirect method of counting virus particles is by |
| A. | hemagglutination assay |
| B. | plaque-assay |
| C. | counting plaque-forming units |
| D. | colony counting |
| Answer» B. plaque-assay | |
| 2. |
What kind of embryo is often used for viral assays? |
| A. | Mouse |
| B. | Rat |
| C. | Cat |
| D. | Chicken |
| Answer» E. | |
| 3. |
The size of viruses is usually measured in |
| A. | centimeters |
| B. | micrometers |
| C. | nanometers |
| D. | millimeters |
| Answer» D. millimeters | |
| 4. |
In order for a virus to replicate |
| A. | the capsid must enter the host cell cytoplasm |
| B. | the host cell must be undergoing mitosis |
| C. | the genome must be released in the cytoplasm |
| D. | the host cell must lack a cell membrane |
| Answer» D. the host cell must lack a cell membrane | |
| 5. |
The envelope of an enveloped virus is derived from |
| A. | the mitochondrion of the cell |
| B. | the cell membrane |
| C. | the endoplasmic reticulum of the cell |
| D. | none of these |
| Answer» C. the endoplasmic reticulum of the cell | |
| 6. |
Which one is not useful in the treatment of viruses except |
| A. | acyclovir |
| B. | interferon |
| C. | penicillin |
| D. | antibodies |
| Answer» D. antibodies | |
| 7. |
Which of the following oncogenic viruses was first detected? |
| A. | Rous sarcoma virus. |
| B. | Epstein-Barr virus |
| C. | Herpes simplex virus type 2 |
| D. | Human T cell leukaemia virus |
| Answer» B. Epstein-Barr virus | |
| 8. |
Viruses can be purified based on their size and density by using |
| A. | gradient centrifugation |
| B. | differential centrifugation |
| C. | precipitation |
| D. | none of these |
| Answer» B. differential centrifugation | |
| 9. |
Which of the following are obligate intracellular parasites? |
| A. | Chlamydia |
| B. | Viruses |
| C. | Rickettsia |
| D. | All of these |
| Answer» E. | |
| 10. |
Inclusion bodies of measles virus are |
| A. | intracytoplasmic |
| B. | intranuclear |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 11. |
Which of the following viruses can rescue adenovirus in simian cells? |
| A. | Rabies |
| B. | Vaccinia |
| C. | Simian virus 40 |
| D. | Cytomegalovirus |
| Answer» D. Cytomegalovirus | |
| 12. |
Which of the following is continuous cell line? |
| A. | HeLa |
| B. | HEp-2 |
| C. | KB |
| D. | All of these |
| Answer» E. | |
| 13. |
Which of the following virus is susceptible to chloroform? |
| A. | Herpes |
| B. | Influenza |
| C. | Measles |
| D. | All of these |
| Answer» E. | |
| 14. |
Enzyme neuraminidase is carried by which of the following viruses? |
| A. | Human immunodeficiency virus |
| B. | Epstein-Barr virus |
| C. | Influenza virus |
| D. | Adenovirus |
| Answer» D. Adenovirus | |
| 15. |
Which of the following viruses are relatively thermostable? |
| A. | Human immunodeficiency virus |
| B. | Rubella virus |
| C. | Hepatits A virus |
| D. | Influenza virus |
| Answer» D. Influenza virus | |
| 16. |
Which of the following viruses belong/s to family caliciviridae? |
| A. | Hepatitis B virus |
| B. | Hepatitis D virus |
| C. | Hepatitis E virus |
| D. | All of these |
| Answer» D. All of these | |
| 17. |
Which of the following viruses belong to family Hepadnaviridae? |
| A. | Hepatitis A virus |
| B. | Hepatitis B virus |
| C. | Hepatitis D virus |
| D. | All of these |
| Answer» C. Hepatitis D virus | |
| 18. |
Which of the following viruses belong to family Flaviviridae? |
| A. | Rubella virus |
| B. | Yellow fever virus |
| C. | Hepatitis C virus |
| D. | All of these |
| Answer» E. | |
| 19. |
Lesions on chorioallantoic membrane are produced by |
| A. | Herpes B virus |
| B. | Vaccinia virus |
| C. | Herpes simplex virus |
| D. | all of these |
| Answer» E. | |
| 20. |
The most efficient way to enclose a space is within a/an |
| A. | sphere |
| B. | cube |
| C. | icosahedron |
| D. | helix |
| Answer» D. helix | |
| 21. |
Which of the following virus is enveloped? |
| A. | Adeno |
| B. | Herpes |
| C. | Polio |
| D. | None of these |
| Answer» C. Polio | |
| 22. |
The function of a viral capsid is |
| A. | protection against the viral genome from physical and enzymatic destruction |
| B. | providing binding sites that enable the virus to attach to specific receptor sites on the host cell |
| C. | serving as a vehicle of transmission from one host to another |
| D. | all of the above |
| Answer» E. | |
| 23. |
Which of the following is not true of virions? |
| A. | Reproduce independently |
| B. | Contain DNA |
| C. | Contain RNA |
| D. | Are extracellular |
| Answer» B. Contain DNA | |
| 24. |
The temperate phage that have no site specificity for insertion and may even be able to insert multiple copies of their DNA into a single bacterial chromosome is |
| A. | λ phage enzyme |
| B. | λ DNA |
| C. | Phage Mu |
| D. | Phage Mn |
| Answer» D. Phage Mn | |
| 25. |
The repressor protein, since the cell is resistant to lysis from externally infecting phage, is also called |
| A. | immunity repressor |
| B. | immunity operon |
| C. | operon repressor |
| D. | none of these |
| Answer» B. immunity operon | |
| 26. |
The temperate phage possesses a gene that codes for a repressor protein which makes the cell resistant to lysis initiated by |
| A. | the prophage |
| B. | lytic infection by other viruses |
| C. | Both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 27. |
The time from infection until lysis is called as |
| A. | eclipse period |
| B. | rise period |
| C. | latent period |
| D. | burst size |
| Answer» D. burst size | |
| 28. |
During the first 10 minutes after injection of phage DNA, no phage can be recovered by disrupting the infected bacterium. This is termed as |
| A. | eclipse period |
| B. | rise period |
| C. | latent period |
| D. | burst size |
| Answer» B. rise period | |
| 29. |
Lysozyme (an endolysin) which will lyse the bacterial cell, releasing the mature virions is present in |
| A. | immediate early phage genes |
| B. | late genes |
| C. | delayed early genes |
| D. | all of these |
| Answer» C. delayed early genes | |
| 30. |
The phage components begin to assemble into mature phages only after the synthesis of |
| A. | structural protein |
| B. | nucleic acid |
| C. | Both (a) and (b) |
| D. | amino acids |
| Answer» D. amino acids | |
| 31. |
The viral DNA is removed from the host's chromosomes and the lytic cycle occurs. The process is called |
| A. | spontaneous induction |
| B. | inductive infection |
| C. | resultant induction |
| D. | spontaneous infection |
| Answer» B. inductive infection | |
| 32. |
The viral DNA of the temperate phage, instead of taking over the functions of the cell's genes, is incorporated into the host DNA and becomes a prophage in the bacterial chromosome, acting as a gene. This happens in |
| A. | lysogeny |
| B. | spontaneous induction |
| C. | lytic phase |
| D. | none of these |
| Answer» B. spontaneous induction | |
| 33. |
The infected cells continue to reproduce themselves as well as the virus, and the mature virions are extruded from the cell surface continuously over a long period of time. This type of release mechanism is called a |
| A. | productive infection |
| B. | inductive infection |
| C. | resultant infection |
| D. | all of these |
| Answer» B. inductive infection | |
| 34. |
The yield of phage per bacterium is called the |
| A. | eclipse size |
| B. | latent size |
| C. | burst size |
| D. | none of these |
| Answer» D. none of these | |
| 35. |
The extracellular phage number increases until a constant titer at the end of the multiplication cycle. This time interval is termed as |
| A. | eclipse period |
| B. | rise period |
| C. | latent period |
| D. | burst size |
| Answer» C. latent period | |
| 36. |
Which of the following bacteriophage is said to have banal symmetry? |
| A. | T2 |
| B. | T4 |
| C. | T6 |
| D. | all of these |
| Answer» E. | |
| 37. |
Group E phages have |
| A. | single stranded DNA |
| B. | double stranded DNA |
| C. | single stranded RNA |
| D. | double stranded DNA |
| Answer» D. double stranded DNA | |
| 38. |
Which of the following is an example of rod-shaped viruses having their capsomeres arranged helically and not in the stacked ring? |
| A. | Bateriophage M13 |
| B. | Bateriophage MV-L2 |
| C. | Bateriophage T2 |
| D. | Bateriophage T4 |
| Answer» B. Bateriophage MV-L2 | |
| 39. |
In the simplest capsid, there is a capsomere at each of the 12 vertices; this capsomere, which is surrounded by five other capsomeres, is termed a |
| A. | penton |
| B. | polyhedra |
| C. | icosahedral |
| D. | helical |
| Answer» B. polyhedra | |
| 40. |
Bacteriophages have been used widely in genetic research, since they are the smallest and simplest biological entities capable of |
| A. | self-replication |
| B. | duplication |
| C. | self-duplication |
| D. | multiplication |
| Answer» B. duplication | |
| 41. |
The most complex type of bacterial viruses having hexagonal head, a rigid tail with a contractile sheath and tall fibers is morphologically classified as |
| A. | A |
| B. | B |
| C. | C |
| D. | D |
| Answer» B. B | |
| 42. |
The bacterial viruses having head made up of large capsomeres, but no tail is morphologically classified as |
| A. | A |
| B. | B |
| C. | C |
| D. | D |
| Answer» E. | |
| 43. |
Virus reproduces in living cells by |
| A. | replication |
| B. | duplication |
| C. | multiplication |
| D. | all of these |
| Answer» B. duplication | |
| 44. |
The sequence of nucleic acid in a variety of viruses and viral host, will find more similarities |
| A. | among different viruses than between viruses and their hosts |
| B. | among different viral hosts than among different viruses |
| C. | among different viral hosts than between viruses and their hosts |
| D. | between viruses and their hosts than among different viruses |
| Answer» E. | |
| 45. |
Which of the following statements is not true of viruses? |
| A. | Viruses have been successfully grown in pure cultures in test tubes |
| B. | All viruses are obligatory intracellular parasites |
| C. | All viruses have either DNA or RNA as their genetic material |
| D. | Viruses probably arose from small fragments of cellular chromosomes |
| Answer» B. All viruses are obligatory intracellular parasites | |
| 46. |
The development of hepatocellular carcinoma is associated with |
| A. | ground squirrel hepatitis virus |
| B. | hepatitis B virus |
| C. | woodchuck hepatitis virus |
| D. | all of the above |
| Answer» E. | |
| 47. |
Which of the following viruses can be transmitted by the parenteral route? |
| A. | HBV |
| B. | HCV |
| C. | HDV |
| D. | All of these |
| Answer» E. | |
| 48. |
Which of the following is not correct for hepatitis A virus? |
| A. | It can be grown in cell cultures of primate and human cells |
| B. | It is one of the most stable viruses infecting humans |
| C. | It may cause hepatocellular carcinoma |
| D. | None of the above |
| Answer» D. None of the above | |
| 49. |
Which of the following antigenic types of hepatitis B virus is present in the envelope? |
| A. | HbsAg |
| B. | HBcAg |
| C. | HBeAg |
| D. | HBxAg |
| Answer» B. HBcAg | |
| 50. |
The diagnosis of hepatitis A virus infection is carried out from the method based on |
| A. | aminotransferase levels |
| B. | detection of faecal HAV by immunoelectron microscopy |
| C. | both (a) and (b) |
| D. | detection of IgM anti-HAV by ELISA |
| Answer» E. | |