MCQOPTIONS
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MCQOPTIONS
This section includes 20 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In SOS repair system cleavage of LexA and UmuD is mediated by ___________ |
| A. | RecB |
| B. | RecA |
| C. | RecC |
| D. | UvrA |
| Answer» C. RecC | |
| 2. |
In eukaryotes the other name of PCNA is __________ |
| A. | Sliding clamp |
| B. | Sliding clamp loader |
| C. | Replicative DNA polymerase |
| D. | Translesional DNA polymerase |
| Answer» B. Sliding clamp loader | |
| 3. |
The genes encoding the translesional polymerases are expressed as part of a pathway known as the SOS response. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 4. |
In humans which DNA polymerase is involved? |
| A. | DNA polymerase ƞ |
| B. | DNA polymerase α |
| C. | DNA polymerase β |
| D. | DNA polymerase ν |
| Answer» B. DNA polymerase α | |
| 5. |
What is the main enzyme that plays a major role in formation of thymine dimer? |
| A. | DNA glycosylase |
| B. | DNA photolyase |
| C. | DNA gyrase |
| D. | DNA ligase |
| Answer» C. DNA gyrase | |
| 6. |
IN_HUMAN_WHICH_DNA_POLYMERASE_IS_INVOLVED??$ |
| A. | DNA polymerase ∆û |
| B. | DNA polymerase α |
| C. | DNA polymerase β |
| D. | DNA polymerase ν |
| Answer» B. DNA polymerase ‚âà√≠¬¨¬± | |
| 7. |
In eukaryotes the other name of PCNA is __________$ |
| A. | Sliding clamp |
| B. | Sliding clamp loader |
| C. | Replicative DNA polymerase |
| D. | Translesional DNA polymerase |
| Answer» B. Sliding clamp loader | |
| 8. |
The_genes_encoding_the_translesional_polymerases_are_expressed_as_part_of_a_pathway_known_as_the_SOS_response.$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 9. |
In the following compounds which are involved in nucleotide excision repair? |
| A. | UvrA, UvrB, UvrC |
| B. | UvrC, UvrD |
| C. | Uvr C, XPA, XPD |
| D. | XPA, XPC, XPD, XPG |
| Answer» E. | |
| 10. |
NHEJ is ubiquitin independent in eukaryotic organisms. |
| A. | True |
| B. | False |
| Answer» C. | |
| 11. |
What are the two fundamental components of NHEJ? |
| A. | KU70, KU80 |
| B. | KU50, KU70 |
| C. | KU40, KU50 |
| D. | KU30, KU40 |
| Answer» B. KU50, KU70 | |
| 12. |
In_SOS_repair_system_cleavage_of_LexA_and_UmuD_is_mediated_by____________ |
| A. | RecB |
| B. | RecA |
| C. | RecC |
| D. | UvrA |
| Answer» C. RecC | |
| 13. |
Which complex in E. coli performs in translesion synthesis? |
| A. | DNA polymerase IV, DNA polymerase V |
| B. | DNA polymerase II, DNA polymerase III |
| C. | DNA polymerase III, DNA polymerase IV |
| D. | DNA polymerase V, RNA polymerase I |
| Answer» B. DNA polymerase II, DNA polymerase III | |
| 14. |
After creation of the bubble which Uvr component are recruited? |
| A. | Uvr B |
| B. | Uvr A |
| C. | Uvr C |
| D. | Uvr D |
| Answer» D. Uvr D | |
| 15. |
Which two Uvr component molecules scan the DNA during nucleotide excision repair? |
| A. | UvrC, UvrA |
| B. | UvrA, UvrB |
| C. | UvrB, UvrC |
| D. | UvrD, UvrA |
| Answer» C. UvrB, UvrC | |
| 16. |
What is the main enzyme that plays the major role in formation of thymine dimer? |
| A. | DNA glycosylase |
| B. | DNA photolyase |
| C. | DNA gyrase |
| D. | DNA ligase |
| Answer» C. DNA gyrase | |
| 17. |
Which enzyme is activated during double stranded break? |
| A. | DNA polymerase |
| B. | Translesional polymerase |
| C. | RNA polymerase |
| D. | Klenow fragment |
| Answer» C. RNA polymerase | |
| 18. |
Why recombinational repair system is called double strand break repair? |
| A. | Both strands are broken |
| B. | One strand is broken |
| C. | No strand is broken |
| D. | Both strand act as template |
| Answer» B. One strand is broken | |
| 19. |
How many types of excision repair systems are known? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 20. |
What is the correct definition of excision repair? |
| A. | Repair of a single damaged nucleotide |
| B. | Repair of a damaged oligonucleotide |
| C. | Removal of a single damaged nucleotide |
| D. | Removal of a damaged oligonucleotide |
| Answer» D. Removal of a damaged oligonucleotide | |