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This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Analytical Instrumentation knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following types of liquid chromatography uses immobilized biochemical as a stationary phase? |
| A. | Ion exchange chromatography |
| B. | Exclusion chromatography |
| C. | Affinity chromatography |
| D. | Gel permeation chromatography |
| Answer» D. Gel permeation chromatography | |
| 2. |
Which of the following is not true about narrow bore column when compared to standard columns? |
| A. | Internal diameter decreases |
| B. | Volumetric flow decreases |
| C. | Solvent cost is saved |
| D. | Detector response time increases |
| Answer» E. | |
| 3. |
Which of the following is not true about the radial compression column when compared to standard separation column? |
| A. | Internal diameter decreases |
| B. | Overall operating pressure decreases |
| C. | Analysis time decreases |
| D. | Solvent flow increases |
| Answer» B. Overall operating pressure decreases | |
| 4. |
Which of the following is not true about the guard column used in liquid chromatography? |
| A. | It filters particles that clog the separation column |
| B. | It extends the lifetime of separation column |
| C. | It allows particles that cause precipitation upon contact with stationary or mobile phase |
| D. | The size of packing varies with the type of protection needed |
| Answer» D. The size of packing varies with the type of protection needed | |
| 5. |
Which of the following will improve the efficiency of the separation process in liquid chromatography? |
| A. | Increase in sample size, increase in column diameter |
| B. | Reduction in sample size, increase in column diameter |
| C. | Increase in sample size, reduction in column diameter |
| D. | Reduction in sample size, reduction in column diameter |
| Answer» E. | |
| 6. |
WHICH_OF_THE_FOLLOWING_IS_NOT_TRUE_ABOUT_NARROW_BORE_COLUMN_WHEN_COMPARED_TO_STANDARD_COLUMNS??$ |
| A. | Internal diameter decreases |
| B. | Volumetric flow decreases |
| C. | Solvent cost is saved |
| D. | Detector response time increases |
| Answer» E. | |
| 7. |
Which of the following types of liquid chromatography uses immobilized biochemical as stationary phase?$ |
| A. | Ion exchange chromatography |
| B. | Exclusion chromatography |
| C. | Affinity chromatography |
| D. | Gel permeation chromatography |
| Answer» D. Gel permeation chromatography | |
| 8. |
Which of the following is not true about radial compression column when compared to standard separation column? |
| A. | Internal diameter decreases |
| B. | Overall operating pressure decreases |
| C. | Analysis time decreases |
| D. | Solvent flow increases |
| Answer» B. Overall operating pressure decreases | |
| 9. |
Which of the following is not a Column-type Liquid chromatography? |
| A. | Gel permeation |
| B. | Ion exchange |
| C. | Liquid-solid |
| D. | Paper |
| Answer» E. | |
| 10. |
Which of the following columns are not used in liquid or high performance liquid chromatography? |
| A. | Analytical column |
| B. | Separation column |
| C. | Guard column |
| D. | Capillary column |
| Answer» E. | |
| 11. |
Which of the following is not true about guard column used in liquid chromatography? |
| A. | It filters particles that clog the separation column |
| B. | It extends the lifetime of separation column |
| C. | It allows particles that cause precipitation upon contact with stationary or mobile phase |
| D. | The size of packing varies with the type of protection needed |
| Answer» D. The size of packing varies with the type of protection needed | |
| 12. |
Which of the following are the practical problems that arise due to the decrease in column diameter? |
| A. | Requirement of large particle size and high pressure drop |
| B. | Requirement of large particle size and low pressure drop |
| C. | Requirement of small particle size and high pressure drop |
| D. | Requirement of small particle size and low pressure drop |
| Answer» D. Requirement of small particle size and low pressure drop | |
| 13. |
Which of the following will improve the efficiency of separation process in liquid chromatography? |
| A. | Increase in sample size, increase in column diameter |
| B. | Reduction in sample size, increase in column diameter |
| C. | Increase in sample size, reduction in column diameter |
| D. | Reduction in sample size, reduction in column diameter |
| Answer» E. | |
| 14. |
Which of the following is not a desired characteristic of pulse dampers or flow smootheners used in liquid chromatography? |
| A. | Easy mobile phase change over |
| B. | Constant flow must be maintained |
| C. | Should be effective at low system pressure |
| D. | Maximal dead volume |
| Answer» E. | |
| 15. |
Which of the following is not a disadvantage of Pneumatic pumps used in liquid chromatography? |
| A. | Pulsed output |
| B. | Dependent on solvent viscosity |
| C. | Dependent on back pressure |
| D. | Inconvenient for solvent gradient elution |
| Answer» B. Dependent on solvent viscosity | |
| 16. |
Which of the following is the disadvantage of reciprocating pump used in liquid chromatography? |
| A. | Produces pulsed flow |
| B. | Corrosive components |
| C. | Does not have small hold-up value |
| D. | Does not have moderate flow rate |
| Answer» B. Corrosive components | |