Explore topic-wise MCQs in Molecular Biology.

This section includes 22 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.

1.

Alternative splicing can be used to switch off a gene’s expression. How many ways are there to achieve it?

A. 1
B. 2
C. 3
D. 4
Answer» C. 3
Discussion
2.

Which of the following mRNA is an example of having an extended exon?

A. Human slo gene
B. Mammalian muscle Troponin T mRNA
C. T-antigen mRNA of monkey virus SV40
D. Drosophila Dscam mRNA
Answer» D. Drosophila Dscam mRNA
Discussion
3.

Alternative splicing of the Troponin T gene produces ____________ alternative forms of mRNA.

A. 1
B. 2
C. 3
D. 4
Answer» C. 3
Discussion
4.

hnRNPI binds to which segment of the mRNA?

A. 5’ splice site
B. Branch point site
C. 3’ splice site
D. AT – AC splicosome
Answer» D. AT – AC splicosome
Discussion
5.

The pre-mRNA binding minor splicosome is also known as ___________

A. AG – CT splicosome
B. AT – GC splicosome
C. AC – AG splicosome
D. AT – AC splicosome
Answer» E.
Discussion
6.

hrRNPA1 acts as the repressor for the final mRNA form of ____________

A. Adenovirus
B. Insulin
C. SV40
D. HIV
Answer» E.
Discussion
7.

THE_PRE-MRNA_BINDING_MINOR_SPLICOSOME_IS_ALSO_KNOWN_AS____________?$

A. AG – CT splicosome
B. AT – GC splicosome
C. AC – AG splicosome
D. AT – AC splicosome
Answer» E.
Discussion
8.

Alternative splicing of the Troponin T gene produces ____________ alternative forms of mRNA.$

A. 1
B. 2
C. 3
D. 4
Answer» C. 3
Discussion
9.

hnRNPI_binds_to_which_segment_of_the_mRNA?$

A. 5’ splice site
B. Branch point site
C. 3’ splice site
D. AT – AC splicosome
Answer» D. AT ‚Äö√Ñ√∂‚àö√ë‚àö¬® AC splicosome
Discussion
10.

Which of the following is not a part of the minor splicosome machinery?

A. U2
B. U4
C. U5
D. U6
Answer» B. U4
Discussion
11.

Alternative splicing was discovered in the year ______________

A. 1977
B. 1958
C. 1964
D. 1982
Answer» B. 1958
Discussion
12.

Alternative splicing can be used to switch off a gene’s expression. How many ways are there to achieve it?$

A. 1
B. 2
C. 3
D. 4
Answer» C. 3
Discussion
13.

Alternative splicing is always used to produce multiple isoforms of proteins.

A. True
B. False
Answer» C.
Discussion
14.

Which_of_the_following_mRNA_is_an_example_of_having_an_extended_exon?

A. Human slo gene
B. Mammalian muscle Troponin T mRNA
C. T-antigen mRNA of monkey virus SV40
D. Drosophila Dscam mRNA
Answer» D. Drosophila Dscam mRNA
Discussion
15.

hrRNPA1 acts as the repressor for the final mRNA form of ___________?

A. Adenovirus
B. Insulin
C. SV40
D. HIV
Answer» E.
Discussion
16.

Most silencer proteins are able to bind to pre-mRNA but cannot recruit the splicing machinery.

A. True
B. False
Answer» B. False
Discussion
17.

The Drosophila half-pint protein is _____________

A. Positive regulator
B. Negative regulator
C. Non regulator
D. Not related to fly ovarian protein
Answer» B. Negative regulator
Discussion
18.

Alternative splicing is regulated by activators and repressors.

A. True
B. False
Answer» B. False
Discussion
19.

The presence and activity of SR determines the ___________

A. Product formed after splicing
B. Mechanism of splicing
C. Usage of particular splice site
D. Repression of splicing mechanism
Answer» D. Repression of splicing mechanism
Discussion
20.

SR proteins are not essential for RNA splicing.

A. True
B. False
Answer» C.
Discussion
21.

Which of the following components of the splicosome machinery is recruited by the SR protein?

A. U4
B. U2
C. U2AF
D. U6
Answer» D. U6
Discussion
22.

How many types of specific domains are present in the SR protein?

A. 1
B. 2
C. 3
D. 0
Answer» C. 3
Discussion