MCQOPTIONS
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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Attenuator in the tryptophan operon is the __________ |
| A. | Operator sequence |
| B. | Non-transcribed region within the operon |
| C. | Leader sequence for the site of RNA polymerase binding |
| D. | Leader sequence in the tryptophan mRNA coding for many tryptophan residues |
| Answer» E. | |
| 2. |
Which of the following is false about bacterial tryptophan operon? |
| A. | It has two kinds of regulation system |
| B. | The co-repressor is the catabolite activator protein |
| C. | When tryptophan supply is insufficient the tryptophan operon activates |
| D. | The complex of repressor with co-repressor on binding to the operator blocks transcription |
| Answer» C. When tryptophan supply is insufficient the tryptophan operon activates | |
| 3. |
In the case of lac operon, the gene expression is inhibited by __________ |
| A. | Presence of lactose |
| B. | Interaction of repressor with lactose |
| C. | Interaction of repressor with operator |
| D. | Interaction of lactose with operator |
| Answer» D. Interaction of lactose with operator | |
| 4. |
Mutation in the regulatory gene of a positively controlled operon can be identified by __________ |
| A. | Operon induction |
| B. | Operon repression |
| C. | High expression |
| D. | Constitutive expression |
| Answer» C. High expression | |
| 5. |
What effect would a loss-of-function mutation have on the expression of the gene encoding the catabolite activator protein of the lac operon? |
| A. | Low expression in the presence of lactose and off in its absence, regardless of the presence or absence of glucose |
| B. | High expression in the presence of lactose and off in its absence, regardless of the presence or absence of glucose |
| C. | Low expression in the presence of glucose and off in its absence, regardless of the presence or absence of lactose |
| D. | High expression in the presence of glucose and off in its absence, regardless of the presence or absence of lactose |
| Answer» B. High expression in the presence of lactose and off in its absence, regardless of the presence or absence of glucose | |
| 6. |
The complete expression of the lac operon requires __________ |
| A. | Lactose |
| B. | Allolactose |
| C. | Lactose and cAMP |
| D. | Allolactose and cAMP |
| Answer» E. | |
| 7. |
If there is an insertion mutation in the operator of the lac operon, the expression of the lac structural gene will be __________ |
| A. | Resistant to catabolic expression |
| B. | Unexpressed |
| C. | Constitutively expressed |
| D. | Permanently disabled |
| Answer» D. Permanently disabled | |
| 8. |
According to the repressor of lac operon which of the following are false? |
| A. | It is the gene product of the regulatory gene |
| B. | It binds to the promoter region |
| C. | It blocks the transcription of structural genes |
| D. | It combines with allolactose and thus does not bind to the operon |
| Answer» C. It blocks the transcription of structural genes | |
| 9. |
Lac operon follows a trans-acting control mechanism. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 10. |
If the lac operon of the genome of bacteria is always active it has a defect in which region of the operon? |
| A. | i |
| B. | o |
| C. | Promoter |
| D. | Structural gene |
| Answer» B. o | |
| 11. |
Defects in which regions can affect the activity of the lac operon? |
| A. | Promoter |
| B. | i |
| C. | Terminator |
| D. | i and o |
| Answer» E. | |
| 12. |
How many enzymes are produced in the lac operon under the same promoter? |
| A. | 4 |
| B. | 3 |
| C. | 2 |
| D. | 1 |
| Answer» C. 2 | |
| 13. |
Presence of lactose itself induces the production of -galactoside transferase. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 14. |
The investigation of the lac operon for the metabolism of lactose was done by __________ |
| A. | Gilbert |
| B. | Walter Gilbert |
| C. | Francois Jacob and Jacques Monod |
| D. | Walter |
| Answer» D. Walter | |
| 15. |
The functional unit in which genes are arranged consecutively is known as ___________ |
| A. | Induction system |
| B. | An end product repression system |
| C. | A consecutive enzyme system |
| D. | Operon |
| Answer» E. | |