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This section includes 17 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Passage of a cell through stages of cell cycle is controlled by a protein kinase that phosphorylates many different proteins at appropriate times. |
| A. | Cdk activating kinase |
| B. | Cyclin-dependent kinase |
| C. | Cyclins |
| D. | Tyrosine kinase |
| Answer» C. Cyclins | |
| 2. |
Which of the following occurs in meiosis but not in mitosis? |
| A. | Attachment of spindle fibers to kinetochore |
| B. | Replication of DNA prior to start of cell division |
| C. | Separation of sister chromatids at anaphase |
| D. | Pairing of homologous chromosomes at metaphase plate |
| Answer» E. | |
| 3. |
At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damaged? |
| A. | G1 – S |
| B. | S – G2 |
| C. | G2 – M |
| D. | G0 – G1 |
| Answer» B. S – G2 | |
| 4. |
At the end of each phase of cell cycle cyclins activating Cdks in that phase are inactivated irreversibly by _____________ |
| A. | Multiple phosphorylations |
| B. | De-phosphorylation |
| C. | Ubiquitinylation |
| D. | Destabilizing by proteolysis in a proteosome |
| Answer» E. | |
| 5. |
Cyclin dependent kinases which control progression through cell cycle checkpoints are totally activated by which of the following? |
| A. | Binding to cyclin, plus phosphorylation by a Cdk activating protein kinase |
| B. | Binding to cyclins |
| C. | Phosphorylation by Cdk activating protein kinase |
| D. | Phosphorylation by a tyrosine kinase |
| Answer» B. Binding to cyclins | |
| 6. |
Cdk2/cyclinE functions in ____________ |
| A. | G2/M transition |
| B. | G2 |
| C. | M |
| D. | G1/S transition |
| Answer» E. | |
| 7. |
What is Ubiquitin? |
| A. | Protein kinase |
| B. | Protease |
| C. | Component of the electron transport system |
| D. | Protein that tags another protein for proteolysis |
| Answer» E. | |
| 8. |
WHICH_OF_THE_FOLLOWING_OCCURS_IN_MEIOSIS_BUT_NOT_IN_MITOSIS??$ |
| A. | Attachment of spindle fibers to kinetochore |
| B. | Replication of DNA prior to start of cell division |
| C. | Separation of sister chromatids at anaphase |
| D. | Pairing of homologous chromosomes at metaphase plate |
| Answer» E. | |
| 9. |
Passage_of_a_cell_through_stages_of_cell_cycle_is_controlled_by_a_protein_kinase_that_phosphorylates_many_different_proteins_at_appropriate_times$ |
| A. | Cdk activating kinase |
| B. | Cyclin-dependent kinase |
| C. | Cyclins |
| D. | Tyrosine kinase |
| Answer» C. Cyclins | |
| 10. |
At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damage?# |
| A. | G<sub>1</sub> – S |
| B. | S – G<sub>2</sub> |
| C. | G<sub>2</sub> – M |
| D. | G<sub>0</sub> – G<sub>1</sub> |
| Answer» B. S ‚Äö√Ñ√∂‚àö√ë‚àö¬® G<sub>2</sub> | |
| 11. |
At the end of each phase of cell cycle cyclins activating Cdks in that phase are inactivated irreversibly by |
| A. | Multiple phosphorylations |
| B. | De-phosphorylation |
| C. | Ubiquitinylation |
| D. | Destabilizing by proteolysis in a proteosome |
| Answer» E. | |
| 12. |
Cyclin dependent kinases which control progression through cell cycle checkpoints are totally activated by which of the following |
| A. | Binding to cyclin, plus phosphorylation by a Cdk activating protein kinase |
| B. | Binding to cyclins |
| C. | Phosphorylation by Cdk activating protein kinase |
| D. | Phosphorylation by a tyrosine kinase |
| Answer» B. Binding to cyclins | |
| 13. |
In which phase of cell cycle is DNA replicated? |
| A. | G<sub>1</sub> phase |
| B. | S phase |
| C. | G<sub>2</sub> phase |
| D. | M phase |
| Answer» C. G<sub>2</sub> phase | |
| 14. |
Cdk2/cyclinE functions in |
| A. | G<sub>2</sub>/M transition |
| B. | G<sub>2</sub> |
| C. | M |
| D. | G<sub>1</sub>/S transition |
| Answer» E. | |
| 15. |
Ubiquitin is a |
| A. | Protein kinase |
| B. | Protease |
| C. | Component of the electron transport system |
| D. | Protein that tags another protein for proteolysis |
| Answer» E. | |
| 16. |
Which of the following statements regarding cyclins is not correct? |
| A. | They can become linked to ubiquitin |
| B. | They catalyze the phosphorylation of protein |
| C. | They contain specific amino acid sequence that target them for proteolysis |
| D. | They are activated and degraded during cell cycle |
| Answer» E. | |
| 17. |
Which of the following statements regarding cyclin-dependent protein kinase is not correct? |
| A. | Their activity is regulated by cyclins |
| B. | They can alter the activity of proteins involve in the progression of cells through cell cycle |
| C. | Their activity fluctuates during cell cycle |
| D. | Each type of cell contains one specific form |
| Answer» D. Each type of cell contains one specific form | |