MCQOPTIONS
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This section includes 18 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Ras protein is a ____________ |
| A. | G-protein switch |
| B. | Small monomeric GTPase switch protein |
| C. | Serine-threonine kinase |
| D. | Tyrosine kinase |
| Answer» C. Serine-threonine kinase | |
| 2. |
Which of the following is a short-lived messenger that acts by stimulating a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG? |
| A. | NO |
| B. | NO2 |
| C. | NO3– |
| D. | N2O |
| Answer» B. NO2 | |
| 3. |
Which of the following is not responsible of producing diarrhea? |
| A. | Elevation in [cGMP] |
| B. | Increase in Cl– secretion |
| C. | Decrease in reabsorption of water by the intestinal epithelium |
| D. | Decrease in Cl– secretion |
| Answer» E. | |
| 4. |
cGMP-dependent protein kinase is also called ____________ |
| A. | Protein kinase B |
| B. | Protein kinase A |
| C. | Protein kinase G |
| D. | Protein kinase C |
| Answer» D. Protein kinase C | |
| 5. |
Activation of guanylyl cyclase produces ____________ |
| A. | Guanosine 3’, 5’-cyclic monophosphate |
| B. | Guanosine 2’, 5’-cyclic monophosphate |
| C. | Guanosine 4’, 5’-cyclic monophosphate |
| D. | Guanosine 1’, 5’-cyclic monophosphate |
| Answer» B. Guanosine 2’, 5’-cyclic monophosphate | |
| 6. |
Protein kinase ERK is activated by phosphorylation of ____________ |
| A. | Only Thr |
| B. | Only Tyr |
| C. | Both Thr and Tyr |
| D. | Only Ser |
| Answer» D. Only Ser | |
| 7. |
The enzyme activated by cyclic AMP, passing on the hormonal signal is ____________ |
| A. | Protein kinase B |
| B. | Protein kinase A |
| C. | Protein kinase C |
| D. | G protein receptor kinase |
| Answer» C. Protein kinase C | |
| 8. |
cAMP and cGMP are derived from ____________ |
| A. | ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively |
| B. | ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively |
| C. | GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively |
| D. | None of the mentioned |
| Answer» C. GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively | |
| 9. |
SH2 domain specifically binds to _____________ |
| A. | GDP |
| B. | Ca+2 |
| C. | Phosphorylated tyrosine residues |
| D. | Phosphorylated serine residues |
| Answer» D. Phosphorylated serine residues | |
| 10. |
WHICH_OF_THE_FOLLOWING_IS_A_SHORT-LIVED_MESSENGER_THAT_ACTS_BY_STIMULATING_A_SOLUBLE_GUANYLYL_CYCLASE,_RAISING_[CGMP]_AND_STIMULATING_PKG??$ |
| A. | NO |
| B. | NO<sub>2</sub> |
| C. | NO<sub>3</sub><sup>–</sup> |
| D. | N<sub>2</sub>O |
| Answer» B. NO<sub>2</sub> | |
| 11. |
Ras protein is a$ |
| A. | G-protein switch |
| B. | Small monomeric GTPase switch protein |
| C. | Serine-threonine kinase |
| D. | Tyrosine kinase |
| Answer» C. Serine-threonine kinase | |
| 12. |
cGMP-dependent protein kinase is also called |
| A. | Protein kinase B |
| B. | Protein kinase A |
| C. | Protein kinase G |
| D. | Protein kinase C |
| Answer» D. Protein kinase C | |
| 13. |
Activation of guanylyl cyclase produces |
| A. | Guanosine 3’, 5’-cyclic monophosphate |
| B. | Guanosine 2’, 5’-cyclic monophosphate |
| C. | Guanosine 4’, 5’-cyclic monophosphate |
| D. | Guanosine 1’, 5’-cyclic monophosphate |
| Answer» B. Guanosine 2‚Äö√Ñ√∂‚àö√ë‚àö¬•, 5‚Äö√Ñ√∂‚àö√ë‚àö¬•-cyclic monophosphate | |
| 14. |
Protein kinase ERK is activated by phosphorylation of |
| A. | Only Thr |
| B. | Only Tyr |
| C. | Both Thr and Tyr |
| D. | Only Ser |
| Answer» D. Only Ser | |
| 15. |
The enzyme activated by cyclic AMP, passing on the hormonal signal is |
| A. | Protein kinase B |
| B. | Protein kinase A |
| C. | Protein kinase C |
| D. | G protein receptor kinase |
| Answer» C. Protein kinase C | |
| 16. |
Which of the following is false about phosphorylation by IRS on serine residue? |
| A. | It is an inhibitory phosphorylation |
| B. | It is molecular mechanism for insulin resistance |
| C. | It increases insulin levels |
| D. | Target tissues fail to respond to circulating insulin |
| Answer» D. Target tissues fail to respond to circulating insulin | |
| 17. |
cAMP and cGMP are derived from |
| A. | ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively |
| B. | ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively |
| C. | GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively |
| D. | None |
| Answer» C. GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively | |
| 18. |
SH2 domain specifically binds to |
| A. | GDP |
| B. | Ca<sup>+2</sup> |
| C. | Phosphorylated tyrosine residues |
| D. | Phosphorylated serine residues |
| Answer» D. Phosphorylated serine residues | |