Explore topic-wise MCQs in Biochemistry.

This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the following is true about ribonucease?

A. Native state which is catalytically inactive is denatured
B. Unfolded state is inactive
C. Renatured ribonuclease is inactive
D. Renaturation involves reestablishment of the correct disulfide cross links
Answer» B. Unfolded state is inactive
Discussion
2.

Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true?

A. Protein B serves as precursor for protein A
B. Protein B serves as molecular chaperon for protein A
C. Protein B serves as ligand for protein A
D. Protein B serves as structural motif for protein A
Answer» C. Protein B serves as ligand for protein A
Discussion
3.

Process of folding does not depend on ____________

A. Concentration of salts
B. pH
C. Solute
D. Solvent
Answer» D. Solvent
Discussion
4.

A process by which a protein structure assumes its functional shape or conformation is?

A. Denaturing
B. Folding
C. Synthesis
D. Hydrolysis
Answer» C. Synthesis
Discussion
5.

WHICH_OF_THE_FOLLOWING_IS_TRUE_ABOUT_RIBONUCEASE??$

A. Native state which is catalytically inactive is denatured
B. Unfolded state is inactive
C. Renatured ribonuclease is inactive
D. Renaturation involves reestablishment of the correct disulfide cross links
Answer» B. Unfolded state is inactive
Discussion
6.

PROTEIN_A_WILL_FOLD_INTO_ITS_NATIVE_STATE_ONLY_WHEN_PROTEIN_B_IS_ALSO_PRESENT_IN_THE_SOLUTION._HOWEVER_PROTEIN_B_CAN_FOLD_ITSELF_INTO_NATIVE_CONFIRMATION_WITHOUT_THE_PRESENCE_OF_PROTEIN_A._WHICH_OF_THE_FOLLOWING_IS_TRUE??$

A. Protein B serves as precursor for protein A
B. Protein B serves as molecular chaperon for protein A
C. Protein B serves as ligand for protein A
D. Protein B serves as structural motif for protein A
Answer» C. Protein B serves as ligand for protein A
Discussion
7.

Which of the following about spontaneous folding is false?

A. It involves initial formation of highly compact structure
B. It involves initial formation of a local secondary structure
C. It is essentially a random process
D. It may be defective in some human diseases
Answer» D. It may be defective in some human diseases
Discussion
8.

Which of the following are chaperons in E.coli?

A. Hsp70
B. Hsp40
C. DnaA
D. DnaK and DnaJ
Answer» E.
Discussion
9.

As folding progresses which of the following does not take place?

A. Entropy decreases
B. Amount of protein in native state increases
C. Free energy increases
D. Amount of protein in native state decreases
Answer» E.
Discussion
10.

Which of the following is a function of chaperone protein?

A. It degrades proteins that have folded improperly
B. It provide a template for how the proteins should fold
C. It rescues proteins that have folded improperly and allows them to refold properly
D. It degrades proteins that have folded properly
Answer» D. It degrades proteins that have folded properly
Discussion
11.

Which of the following cannot denature a protein?

A. Iodoacetic acid
B. SDS detergent
C. Urea
D. Heating to 90°C
Answer» B. SDS detergent
Discussion
12.

Process of folding does not depend on

A. Concentration of salts
B. pH
C. Solute
D. Solvent
Answer» D. Solvent
Discussion
13.

A process by which a protein structure assumes its functional shape or conformation is

A. Denaturing
B. Folding
C. Synthesis
D. Hydrolysis
Answer» C. Synthesis
Discussion
14.

Which of the following forces is favorable for protein folding?

A. Hydrophobic interactions
B. Hydrogen bonding
C. Vander Waals forces
D. Ionic bonding
Answer» B. Hydrogen bonding
Discussion