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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
What is the equation for bioavailability? |
| A. | [AUC]std Dstd τtest / [AUC]test Dtest τstd |
| B. | [AUC]test Dtest τstd / [AUC]std Dstd τtest |
| C. | [AUC]test Dstd τtest / [AUC]std Dtest τstd |
| D. | 1 / [AUC]std Dtest τstd |
| Answer» D. 1 / [AUC]std Dtest τstd | |
| 2. |
What kind of substances cannot permeate membranes by passive diffusion? |
| A. | Lipid-soluble |
| B. | Non-ionized substances |
| C. | Hydrophobic substances |
| D. | Hydrophilic substances |
| Answer» E. | |
| 3. |
For the calculation of the volume of distribution (Vd) one take into account: |
| A. | Concentration of a substance in urine |
| B. | Concentration of substance in plasma |
| C. | A daily dose of drug |
| D. | Therapeutic width of drug action |
| Answer» C. A daily dose of drug | |
| 4. |
In carrier mediated transport energy is derived from…….. |
| A. | Hydrolysis of ATP |
| B. | Protein metabolism |
| C. | Concentration gradient |
| D. | All of the above |
| Answer» B. Protein metabolism | |
| 5. |
Cell membrane can pass easily Oxygen and Carbon dioxide. |
| A. | False |
| B. | True |
| C. | none |
| D. | all |
| Answer» C. none | |
| 6. |
What is the pH range of the intestine? |
| A. | 4-5 |
| B. | 1-3 |
| C. | 1-8 |
| D. | 5-8 |
| Answer» E. | |
| 7. |
Which of the following promotes excretion of acidic drugs? |
| A. | Citrates |
| B. | Ammonium chloride |
| C. | Methionine |
| D. | Ascorbic acid |
| Answer» B. Ammonium chloride | |
| 8. |
What does the graph of Rate of Drug dissolution v/s Compression force with this type of curve interpret? |
| A. | Tight binding of the molecules in drug |
| B. | Deformation of the drug particles into smaller particles |
| C. | The influence of compression force on the dissolution rate is difficult |
| D. | Both tight bonding and deformation of the drug molecules |
| Answer» B. Deformation of the drug particles into smaller particles | |
| 9. |
Disease state of a patient can influence drug distribution across the body. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» B. False | |
| 10. |
What helps in the passing of inorganic ions? |
| A. | Ion channels |
| B. | Voltage gated channels |
| C. | Aqueous filled pores |
| D. | Diffusion |
| Answer» D. Diffusion | |
| 11. |
Which one of the following has a high perfusion rate? |
| A. | Fat |
| B. | Muscle and skin |
| C. | Lungs and kidney |
| D. | Bone |
| Answer» D. Bone | |
| 12. |
For a drug that is eliminated primarily by renal glomerular filtration, the theoretical maximumclearance is approximately |
| A. | 1-2 milliliters/min |
| B. | 12 milliliters/min |
| C. | 120 milliliters/min |
| D. | 1200 milliliters/min |
| Answer» D. 1200 milliliters/min | |
| 13. |
………..is defined as volume of blood or plasma from drug is removed in unit time |
| A. | half life |
| B. | clearance |
| C. | volume of distribution |
| D. | biotr |
| Answer» B. clearance | |
| 14. |
When Km |
| A. | Km – C = C |
| B. | Km + C = C |
| C. | Km + C = Km |
| D. | Km - C = Km |
| Answer» C. Km + C = Km | |
| 15. |
Which one of these is not an example of hydrophilic diluents? |
| A. | PVC |
| B. | Dextrose |
| C. | PVP |
| D. | PEG |
| Answer» B. Dextrose | |
| 16. |
Drugs in suspension and semisolid formulations always degrade by - |
| A. | First orer kinetics |
| B. | Second order kinetics |
| C. | Zero order kinetics |
| D. | Non linear kinetics |
| Answer» D. Non linear kinetics | |
| 17. |
Example of market product of soft shell capsule is |
| A. | Phudin hara |
| B. | Seven Seas Capsule |
| C. | Both (Phudin hara) and (Seven Seas Capsule) |
| D. | None |
| Answer» D. None | |
| 18. |
Cascade impactor is used to evaluate : |
| A. | Oral drug delivery system |
| B. | Parenteral drug delivery system |
| C. | Pulmonary drug delivery system |
| D. | None |
| Answer» D. None | |
| 19. |
Consistency of lipstick can be measured by |
| A. | Penetrometer |
| B. | Cup & Bob viscometer |
| C. | Brookfield viscometer |
| D. | All |
| Answer» B. Cup & Bob viscometer | |
| 20. |
Flowability of powder is also expressed as |
| A. | Angle of repose |
| B. | Dustibility |
| C. | Co-efficient of friction |
| D. | All |
| Answer» E. | |
| 21. |
Degradation of suspension follows : |
| A. | First order kinetics |
| B. | Zero order kinetics |
| C. | Non linear kinetics |
| D. | All |
| Answer» C. Non linear kinetics | |
| 22. |
The dissolution media for C.R. dosage form are of gradient pH of |
| A. | 1.2, 4.5, 6.8, 7.2 |
| B. | 1.2, 6.8, 7.8 |
| C. | 1.2, 7.2, 7.8 |
| D. | None |
| Answer» B. 1.2, 6.8, 7.8 | |
| 23. |
Sigma blade mixer is commonly used in |
| A. | Wet granulation |
| B. | Dry granulation |
| C. | Powder mixing |
| D. | Crude fiber mixing |
| Answer» D. Crude fiber mixing | |
| 24. |
Delayed release system is: |
| A. | Enteric coated tablets |
| B. | Orally disintegrating tablets |
| C. | Sugar coated tablets |
| D. | None |
| Answer» B. Orally disintegrating tablets | |
| 25. |
Prodrug of Ampicillin is : |
| A. | Naloxane |
| B. | Pirampicillin |
| C. | Chloramphenicol palmitate |
| D. | Cloxacilline |
| Answer» C. Chloramphenicol palmitate | |