MCQOPTIONS
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MCQOPTIONS
This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Enzyme Technology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of these is not required for electrophilic catalysis? |
| A. | Mg<sup>2+</sup> |
| B. | Zn<sup>2+</sup> |
| C. | Mn<sup>2+</sup> |
| D. | Ser 195 |
| Answer» B. Zn<sup>2+</sup> | |
| 2. |
_____________ involves donation of electrons from nucleophilic active site residues to a substrate forming a covalent adduct transition state intermediate. |
| A. | General acid-base catalysis |
| B. | Specific acid-base catalysis |
| C. | Electrophilic catalysis |
| D. | Nucleophilic catalysis |
| Answer» E. | |
| 3. |
A type of catalysis which involves covalent intermediate transition state formation between the cationic electrophilic group in the enzyme and the electron rich portion of the substrate is referred to as ____________ |
| A. | general acid-base catalysis |
| B. | electrophilic catalysis |
| C. | nucleophilic catalysis |
| D. | specific acid-base catalysis |
| Answer» C. nucleophilic catalysis | |
| 4. |
Chymotrypsin: Nucleophilic catalysis:: Carboxypeptidase A: __________ |
| A. | General acid-base catalysis |
| B. | Specific acid-base catalysis |
| C. | Electrophilic catalysis |
| D. | Nucleophilic catalysis |
| Answer» D. Nucleophilic catalysis | |
| 5. |
The phenomenon which involves formation of an additional covalent intermediate in a reaction that helps to reduce the energy of later transition states is referred to as ___________ |
| A. | covalent catalysis |
| B. | substrate collision theory |
| C. | general acid-base catalysis |
| D. | specific acid-base catalysis |
| Answer» E. | |
| 6. |
In the catalysis of RNA by Bovine pancreatic RNase A, His 12 acts as proton donor. |
| A. | True |
| B. | False |
| Answer» C. | |
| 7. |
The type of catalysis wherein the proton donation or acceptance is done by water molecule is referred to as _____________ |
| A. | substrate collision theory |
| B. | lock and key model |
| C. | general acid-base catalysis |
| D. | specific acid-base catalysis |
| Answer» E. | |
| 8. |
Which of the following factor has a negative impact on substrate collision theory? |
| A. | Temperature |
| B. | Protonation or Deprotonation |
| C. | Substrate concentration |
| D. | Type of medium |
| Answer» C. Substrate concentration | |
| 9. |
The transition state cannot be achieved by using one of the following methods? |
| A. | Substrate collision theory |
| B. | Lock and key model |
| C. | Acid-base catalysis |
| D. | Covalent catalysis |
| Answer» C. Acid-base catalysis | |
| 10. |
The energy required to attain transition state is referred to as _____________ |
| A. | Gibbs free energy |
| B. | Activation energy |
| C. | Standard free energy change |
| D. | pH |
| Answer» C. Standard free energy change | |
| 11. |
In lock and key model, the enzyme catalyzed reaction may produce an adverse reaction. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 12. |
Daniel Koshland proposed a model for enzyme s reaction mechanism in 1958 which is termed as __________ |
| A. | Induced fit model |
| B. | Lock and key model |
| C. | Henri kinetic model |
| D. | Miachelis Menten kinetic model |
| Answer» B. Lock and key model | |
| 13. |
Which of this is not true for the active site of an enzyme? |
| A. | Active site is constituted by 3 to 4 amino-acids in a big protein structure |
| B. | Active site is mainly constituted by non-polar amino acids for catalysis to take place |
| C. | Water is generally included in the site |
| D. | Active site is a cleft formed by different amino-acids from different positions in an enzyme molecule |
| Answer» D. Active site is a cleft formed by different amino-acids from different positions in an enzyme molecule | |