MCQOPTIONS
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MCQOPTIONS
This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Enzyme Technology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which is the first step involved in chymotrypsin mediated peptide bond hydrolysis? |
| A. | Acylation |
| B. | Specific acid-base catalysis |
| C. | General acid-base catalysis |
| D. | Deacylation |
| Answer» E. | |
| 2. |
The covalent catalysis is aided by one of the following method? |
| A. | General acid-base catalysis |
| B. | Specific acid-base catalysis |
| C. | Nucleophilic catalysis |
| D. | Substrate collision theory |
| Answer» D. Substrate collision theory | |
| 3. |
________________ involves substrates forming transient covalent bond with the residues present in the active site |
| A. | Covalent catalysis |
| B. | Specific acid-base catalysis |
| C. | General acid-base catalysis |
| D. | Lock and key model |
| Answer» B. Specific acid-base catalysis | |
| 4. |
If the catalysis involves participation of small organic molecules, cofactors, and amino-acid side chains from the enzyme is termed as ____________ |
| A. | specific acid base catalysis |
| B. | general acid base catalysis |
| C. | substrate collision theory |
| D. | lock and key model |
| Answer» C. substrate collision theory | |
| 5. |
Which of the following is not explained by molecular orbital steering? |
| A. | The juxtaposition of the side chain groups of amino-acid and the reactive groups of the substrate is not sufficient for proper catalysis |
| B. | Overwhelm the vander waals repulsive forces that happen commonly between them |
| C. | The active residues should guide the groups in the substrate for exact interaction by thermal vibration due to elevated temperature |
| D. | Thermal vibration create motion in the active site amino acid side chain that direct reactive groups in the substrate to interact |
| Answer» D. Thermal vibration create motion in the active site amino acid side chain that direct reactive groups in the substrate to interact | |
| 6. |
The disruption of interactions between substrate and solvent is referred to as __________ |
| A. | desolvation |
| B. | molecular orbital steering |
| C. | protonation |
| D. | deprotonation |
| Answer» B. molecular orbital steering | |
| 7. |
Which of the following is not true for substrate collision theory? |
| A. | Both enzyme and substrate stumble upon each other |
| B. | Both enzyme and substrate provide good molecular orbital interactions |
| C. | Specificity of the substrate binding site |
| D. | Both enzyme and substrate should be flexible in forming transition states |
| Answer» D. Both enzyme and substrate should be flexible in forming transition states | |
| 8. |
When the free energy occurs at standard conditions, it is termed as ______________ |
| A. | Activation energy |
| B. | pK<sub>a</sub> |
| C. | Standard free energy change |
| D. | Gibbs free energy |
| Answer» D. Gibbs free energy | |
| 9. |
The target substrate molecules bind to active site of the enzyme transforming into products through a series of steps known as the ____________ |
| A. | enzyme kinetics |
| B. | enzymatic mechanism |
| C. | chemical kinetics |
| D. | zero order reaction kinetics |
| Answer» C. chemical kinetics | |
| 10. |
In induced fit model, only a specific substrate can bind and produce desirable reaction. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 11. |
The lock and key model deals with flexible nature of enzymes. |
| A. | True |
| B. | False |
| Answer» C. | |
| 12. |
Lock and key model was proposed by ______________ in 1890. |
| A. | Henri |
| B. | Miachelis and Menten |
| C. | Emil Fischer |
| D. | Daniel Koshland |
| Answer» D. Daniel Koshland | |
| 13. |
The study of rates of chemical reactions that are catalyzed by enzymes is referred to as ______________ |
| A. | first order reaction kinetics |
| B. | zero order reaction kinetics |
| C. | chemical kinetics |
| D. | enzyme kinetics |
| Answer» E. | |