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This section includes 27 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Name the coated vesicle which is used to transfer protein from plasma membrane to endosome? |
| A. | Clathrin |
| B. | COP I |
| C. | COP II |
| D. | COP III |
| Answer» B. COP I | |
| 2. |
Which of the following coated vesicle transport protein from ER to Golgi? |
| A. | Clathrin |
| B. | COP II |
| C. | COP I |
| D. | COP III |
| Answer» C. COP I | |
| 3. |
Glycolipids are synthesized in the ER and ____________ |
| A. | Nucleus |
| B. | Golgi complex |
| C. | Mitochondrion |
| D. | Plasma membrane |
| Answer» C. Mitochondrion | |
| 4. |
Hydrophobic transmembrane segments of which proteins are not synthesized in the endoplasmic reticulum? |
| A. | integral membrane proteins |
| B. | lysosomal proteins |
| C. | steroids |
| D. | secretory proteins |
| Answer» B. lysosomal proteins | |
| 5. |
The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment. |
| A. | hydrolyzed bonds |
| B. | hydrophobic bonds |
| C. | disulfide bonds |
| D. | hydrophilic bonds |
| Answer» D. hydrophilic bonds | |
| 6. |
Which of the following enzyme present in the rough endoplasmic reticulum removes the signal sequence from nascent polypeptides? |
| A. | signal oxidase |
| B. | signal peptidase |
| C. | olisaccharyltransferase |
| D. | luciferase |
| Answer» C. olisaccharyltransferase | |
| 7. |
Translocon is a ____________ |
| A. | polypeptide |
| B. | protein channel |
| C. | receptor |
| D. | recognition particle |
| Answer» C. receptor | |
| 8. |
In mammalian cells, the signal recognition particle (SRP) consists of ____ distinct polypeptides and one small RNA molecule. |
| A. | 2 |
| B. | 4 |
| C. | 6 |
| D. | 8 |
| Answer» D. 8 | |
| 9. |
In yeast cells, protein transport across the endoplasmic reticulum membrane occurs __________ |
| A. | perpendicularly |
| B. | discontinuously |
| C. | co-translationally |
| D. | post-translationally |
| Answer» E. | |
| 10. |
In the image below, endoplasmic reticulum is depicted by ________ |
| A. | a |
| B. | b |
| C. | c |
| D. | d |
| Answer» B. b | |
| 11. |
The signal sequence that determines whether a protein will be synthesized on a free ribosome or ribosome attached to endoplasmic reticulum is located at _______ |
| A. | N-terminal |
| B. | C-terminal |
| C. | hydrophobic tail |
| D. | hydrophilic tail |
| Answer» B. C-terminal | |
| 12. |
Sarcoplasmic reticulum is found in ________________ |
| A. | liver cells |
| B. | kidney cells |
| C. | muscle cells |
| D. | neurons |
| Answer» D. neurons | |
| 13. |
Which enzymes are responsible for detoxification of organic compounds carried out by the smooth endoplasmic reticulum? |
| A. | Dehydrogenases |
| B. | Oxygenases |
| C. | Nucleases |
| D. | Ribonucleases |
| Answer» C. Nucleases | |
| 14. |
Detoxification of organic compounds like barbiturates and ethanol in the liver is carried out by ________________ |
| A. | smooth endoplasmic reticulum |
| B. | sarcoplasmic reticulum |
| C. | rough endoplasmic reticulum |
| D. | nucleus |
| Answer» B. sarcoplasmic reticulum | |
| 15. |
All the cells contain the same ratio of rough and smooth endoplasmic reticulum. |
| A. | True |
| B. | False |
| Answer» C. | |
| 16. |
Which of the following biomolecules are not synthesized by the endoplasmic reticulum? |
| A. | Proteins |
| B. | Lipids |
| C. | Nucleic acids |
| D. | Cholesterol |
| Answer» D. Cholesterol | |
| 17. |
The membranes of rough endoplasmic reticulum (RER) and smooth endoplasmic reticulum (SER) are continuous. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 18. |
WHICH_OF_THE_FOLLOWING_COATED_VESICLE_TRANSPORT_PROTEIN_FROM_ER_TO_GOLGI??$ |
| A. | Clathrin |
| B. | COP II |
| C. | COP I |
| D. | COP III |
| Answer» C. COP I | |
| 19. |
Name_the_coated_vesicle_which_is_used_to_transfer_protein_from_plasma_membrane_to_endosome?$ |
| A. | Clathrin |
| B. | COP I |
| C. | COP II |
| D. | COP III |
| Answer» B. COP I | |
| 20. |
Name the sequence which allows the resident protein to retain in ER lumen? |
| A. | KDEL |
| B. | KKXX |
| C. | KLDE |
| D. | KXXK |
| Answer» B. KKXX | |
| 21. |
Name the site where detoxification of xenobiotic compounds takes place? |
| A. | Cytosol |
| B. | RER |
| C. | SER |
| D. | Ribosome |
| Answer» D. Ribosome | |
| 22. |
Which of the following is not the function of Glycosylation? |
| A. | Helps in proper folding of the protein |
| B. | Confer stability in proteins |
| C. | Helps in cell-cell adhesion |
| D. | Synthesis of membrane lipid |
| Answer» E. | |
| 23. |
Name the antibiotic which inhibits the synthesis of oligosaccharides? |
| A. | Tunicamycin |
| B. | Cephalosporins |
| C. | Penicillins |
| D. | Ofloxacin |
| Answer» B. Cephalosporins | |
| 24. |
Endoplasmic reticulum membrane which is associated with ribosomes is called_______ |
| A. | ER lumen |
| B. | Smooth endoplasmic reticulum |
| C. | Rough endoplasmic reticulum |
| D. | Endosome |
| Answer» D. Endosome | |
| 25. |
What is microsome? |
| A. | Compartment of Golgi |
| B. | Smaller ribosomes |
| C. | Small ER compartments |
| D. | Small vesicles of fragmented ER |
| Answer» E. | |
| 26. |
Protein undergoes modifications in ER before reaching their final destination. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 27. |
Which of the following is the largest single membrane-bound intracellular compartment? |
| A. | Ribosome |
| B. | Golgi apparatus |
| C. | Nucleus |
| D. | Endoplasmic reticulum |
| Answer» E. | |