MCQOPTIONS
Saved Bookmarks
MCQOPTIONS
This section includes 12 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following enzyme is responsible for initiating DNA replication? |
| A. | polymerase |
| B. | ligase |
| C. | primase |
| D. | gyrase |
| Answer» D. gyrase | |
| 2. |
Which enzyme joins the Okazaki fragments into a continuous strand? |
| A. | gyrase |
| B. | topoisomerase |
| C. | ligase |
| D. | helicase |
| Answer» D. helicase | |
| 3. |
Who made the discovery that one DNA strand is synthesized discontinuously in fragments? |
| A. | Francis Crick |
| B. | Reiji Okazaki |
| C. | James Watson |
| D. | Louis Pasteur |
| Answer» C. James Watson | |
| 4. |
The lagging strand is synthesized discontinuously. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 5. |
How many copies (approximately) of DNA polymerase III are present in a typical bacterial cell? |
| A. | 10 |
| B. | 50 |
| C. | 100 |
| D. | 200 |
| Answer» B. 50 | |
| 6. |
When was DNA polymerase III discovered as the major enzyme behind DNA replication in bacteria? |
| A. | 1949 |
| B. | 1959 |
| C. | 1969 |
| D. | 1989 |
| Answer» D. 1989 | |
| 7. |
Which enzyme removes the positive supercoils generated when the replication fork? |
| A. | helicase |
| B. | endonuclease |
| C. | exonuclease |
| D. | gyrase |
| Answer» E. | |
| 8. |
Movement of the replication fork generates ________________ in the unreplicated portion of DNA. |
| A. | positive supercoils |
| B. | negative supercoils |
| C. | untranslated regions |
| D. | amino acid substitutions |
| Answer» B. negative supercoils | |
| 9. |
The bacterial oriC is the __________________ |
| A. | specific sequence |
| B. | transcription factor |
| C. | enzyme |
| D. | polypeptide |
| Answer» B. transcription factor | |
| 10. |
Temperature-sensitive mutants can not replicate their chromosomes at non-permissive temperatures. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 11. |
Which isotopes were used by the researchers who first confirmed the semiconservative nature of DNA replication? |
| A. | Nitrogen |
| B. | Carbon |
| C. | Oxygen |
| D. | Sulfur |
| Answer» B. Carbon | |
| 12. |
How many types of replication models were considered before the semiconservative nature of DNA replication was confirmed? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» D. 4 | |