MCQOPTIONS
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MCQOPTIONS
This section includes 46 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Tolerance of self-antigen by B-cells are known as B-cell tolerance. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
The G0 phase is |
| A. | a permanent state of all body cells |
| B. | the state of most cells in an animal body |
| C. | another name for interphase |
| D. | all of the above |
| Answer» C. another name for interphase | |
| 3. |
The term homologous chromosomes |
| A. | refers to replications of the same chromosome |
| B. | is another name for sister chromatids |
| C. | must be haploid |
| D. | means a pair of chromosomes of the same kind, such as sex chromosomes |
| Answer» E. | |
| 4. |
Which of the following begins when pairs of sister chromatids align in the center of the cell? |
| A. | Anaphase |
| B. | Interphase |
| C. | Metaphase |
| D. | Prophase |
| Answer» D. Prophase | |
| 5. |
Cdks bind with __________ , enabling the Cdks to function as enzymes. |
| A. | MPF |
| B. | cyclins |
| C. | histones |
| D. | p53 |
| Answer» C. histones | |
| 6. |
In which of the following phase preparations for genome separation are made? |
| A. | C |
| B. | G1 |
| C. | G2 |
| D. | M |
| Answer» E. | |
| 7. |
Cells which no longer divide (such as certain specialized cells found in the human brain) remain in which phase of the cell cycle? |
| A. | Prophase |
| B. | S phase |
| C. | G0 Phase |
| D. | Gl Phase |
| Answer» D. Gl Phase | |
| 8. |
Which of the following is the normal cell cycle, primarily regulated at checkpoints? |
| A. | Metaphase in mitosis |
| B. | Anaphase, G1 boundary |
| C. | G1-S boundary |
| D. | S-G2 boundary |
| Answer» D. S-G2 boundary | |
| 9. |
Microtubules grow from the poles to kinetochores of each chromatid during |
| A. | prophase |
| B. | metaphase |
| C. | anaphase |
| D. | telophase |
| Answer» B. metaphase | |
| 10. |
How many chromatids are there in a duplicated chromosome? |
| A. | One |
| B. | Two |
| C. | Three |
| D. | Four |
| Answer» C. Three | |
| 11. |
Each chromosome contains two chromatids by the end of the __________ phase in the life cycle of a human cell. |
| A. | C |
| B. | G2 |
| C. | M |
| D. | S |
| Answer» E. | |
| 12. |
Which phase of mitosis is associated with separation of chromatids? |
| A. | Prophase |
| B. | Metaphase |
| C. | Anaphase |
| D. | Telophase |
| Answer» D. Telophase | |
| 13. |
The cell cycle is controlled in most cells by |
| A. | time (after a certain length of time the cell divides) |
| B. | a series of checkpoints |
| C. | cell size (when the cell reaches a certain size, it divides) |
| D. | different cells exhibit different control strategies |
| Answer» E. | |
| 14. |
Which of the following is not a part of a human chromosome in any phase? |
| A. | Centriole |
| B. | Histone |
| C. | Nucleosome |
| D. | Centromere |
| Answer» B. Histone | |
| 15. |
At the center of the cell cycle control system is Cdk, a protein that |
| A. | is phosphorylated to become active |
| B. | binds to different cyclins |
| C. | is only active during mitosis |
| D. | manufactures growth factors |
| Answer» C. is only active during mitosis | |
| 16. |
Which of the following statements about mitosis is incorrect? |
| A. | The daughter nuclei are genetically identical to the parent nucleus |
| B. | Chromosomes separate during anaphase due to the interaction of polar microtubules from opposite poles pushing against each other |
| C. | Chromosomes separate during anaphase when the kinetochore microtubules shorten as they depolymerize |
| D. | Chromosomes move to the metaphase plate using motor proteins, a kind of kinesin, attached to spindle fibers |
| Answer» C. Chromosomes separate during anaphase when the kinetochore microtubules shorten as they depolymerize | |
| 17. |
The term, not related to mitosis is |
| A. | gametes |
| B. | chromosomes |
| C. | DNA replication |
| D. | somatic cells |
| Answer» B. chromosomes | |
| 18. |
The phase of mitosis which is associated with the formation of the nuclear envelope, is |
| A. | prophase |
| B. | metaphase |
| C. | anaphase |
| D. | telophase |
| Answer» E. | |
| 19. |
A nuclear envelope forms around each set of sister chromatids in |
| A. | anaphase |
| B. | metaphase |
| C. | prophase |
| D. | telophase |
| Answer» E. | |
| 20. |
Which of the following triggers the division of activated T lymphocytes? |
| A. | FGF |
| B. | Interlukin 2 |
| C. | PDGF |
| D. | Erythroprotein |
| Answer» C. PDGF | |
| 21. |
At the __________ checkpoint, cell growth is controlled. |
| A. | C |
| B. | G1 |
| C. | G2 |
| D. | S |
| Answer» C. G2 | |
| 22. |
What structure forms as a network of protein cables during cell division? |
| A. | Spindle |
| B. | Aster |
| C. | Kinetochore |
| D. | Chromatid |
| Answer» B. Aster | |
| 23. |
The centromeres move toward the poles in __________ . |
| A. | anaphase |
| B. | interphase |
| C. | metaphase |
| D. | prophase |
| Answer» B. interphase | |
| 24. |
DNA replication is controlled at which of the following checkpoint? |
| A. | G1 |
| B. | G2 |
| C. | M |
| D. | S |
| Answer» B. G2 | |
| 25. |
At which of the following check point, mitosis is controlled? |
| A. | G1 |
| B. | G2 |
| C. | M |
| D. | S |
| Answer» C. M | |
| 26. |
How many chromatids does a diploid body cell contain just prior to cell division? |
| A. | 23 |
| B. | 46 |
| C. | 69 |
| D. | 92 |
| Answer» E. | |
| 27. |
In which phase, each chromosome replicates to produce two sister chromatids? |
| A. | Anaphase |
| B. | Interphase |
| C. | Metaphase |
| D. | Prophase |
| Answer» C. Metaphase | |
| 28. |
Sequences that correctly describes the cell cycle is |
| A. | -> G1-> G2 -> S -> mitosis -> cytokinesis -> |
| B. | -> S -> G2 -> mitosis -> cytokinesis -> G1 -> |
| C. | -> G1 ->S -> G2 -> cytokinesis -> mitosis -> |
| D. | ->cytokinesis-> mitosis -> G1 -> S -> G2 -> |
| Answer» C. -> G1 ->S -> G2 -> cytokinesis -> mitosis -> | |
| 29. |
During which phase, a cleavage furrow is formed in animal cells? |
| A. | C |
| B. | G1 |
| C. | G2 |
| D. | M |
| Answer» B. G1 | |
| 30. |
Which of the following is the primary growth phase of a cell? |
| A. | G1 |
| B. | G2 |
| C. | M |
| D. | G0 |
| Answer» B. G2 | |
| 31. |
A centromere is |
| A. | another name for kinetochore |
| B. | the structure to which microtubules attach |
| C. | a constriction on a chromosome bound to a disk |
| D. | all of the above |
| Answer» E. | |
| 32. |
In the cell cycle replication of the genome occurs in the |
| A. | G1 phase |
| B. | G2 phase |
| C. | M phase |
| D. | S phase |
| Answer» E. | |
| 33. |
Which of the following from a blood clot stimulates the growth of cells in the healing process? |
| A. | EGF |
| B. | PDGF |
| C. | MPF |
| D. | NGF |
| Answer» C. MPF | |
| 34. |
Which phase of mitosis is associated with chromosomes aligned at the center of the cell and centromeres divide? |
| A. | anaphase |
| B. | interphase |
| C. | metaphase |
| D. | prophase |
| Answer» D. prophase | |
| 35. |
The spindle forms in the |
| A. | G1 phase |
| B. | G2 phase |
| C. | M phase |
| D. | S phase |
| Answer» D. S phase | |
| 36. |
The event(s) which does not occur during interphase, is/are |
| A. | Chromatin condenses |
| B. | Protein Synthesis |
| C. | Organelles replication |
| D. | DNA replication |
| Answer» B. Protein Synthesis | |
| 37. |
In prokaryotes, just before the cell divides, the two daughter genomes are attached side by side to the |
| A. | cell membrane |
| B. | replication origin |
| C. | centromeres |
| D. | equatorial plate |
| Answer» B. replication origin | |
| 38. |
TOLERANCE_OF_SELF-ANTIGEN_BY_B-CELLS_ARE_KNOWN_AS_B-CELL_TOLERANCE.?$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 39. |
Mark the one which is NOT used in generating antibody diversity? |
| A. | Combinatorial V(D)J joining |
| B. | Juntional and insertional diversification |
| C. | Somatic hypermutation |
| D. | Binary fission |
| Answer» E. | |
| 40. |
Name the most commonly used monoclonal antibody for treatment of breast cancer? |
| A. | Bradikinins |
| B. | Prostaglandin |
| C. | Erbutir |
| D. | Herceptin |
| Answer» E. | |
| 41. |
Name the drug which is used to isolate hybridoma cells from the media? |
| A. | Amphetamine |
| B. | Opium |
| C. | Aminopterin |
| D. | Cocaine |
| Answer» D. Cocaine | |
| 42. |
Hybridoma technology is used to produce___________ |
| A. | Interferons |
| B. | Monoclonal antibodies |
| C. | Antibodies |
| D. | Immune response |
| Answer» C. Antibodies | |
| 43. |
Out of these, which transcription factor does not take part in B-cell activation? |
| A. | Abl |
| B. | NF- kB |
| C. | Jun |
| D. | Fos |
| Answer» B. NF- kB | |
| 44. |
Which of the following acts as a coreceptor for B-cell activation? |
| A. | CD28 |
| B. | IL-2 |
| C. | IgA |
| D. | CD19 |
| Answer» E. | |
| 45. |
What is the meaning of thymus independent B-cell activation? |
| A. | Without the participation of T-cell |
| B. | Do not mature in the thymus |
| C. | Thymus would not take part in its activation |
| D. | Affinity maturation takes place in the thymus |
| Answer» B. Do not mature in the thymus | |
| 46. |
Which of the following is responsible for B-cell activation? |
| A. | Infection |
| B. | Antibody |
| C. | Antigen |
| D. | Allergy |
| Answer» D. Allergy | |