MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The class of immunoglobulins which can cross the placenta is |
| A. | IgM |
| B. | IgG |
| C. | IgA |
| D. | IgD |
| Answer» C. IgA | |
| 2. |
Self reactive antibodies are not found in significant concentration in normal serum because |
| A. | it is impossible to generate a self-reactive antibody |
| B. | self reactive B cells are killed by CD8 T cells |
| C. | B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide |
| D. | self reactive B cells switch to IgA which is all secreted and not present in serum |
| Answer» D. self reactive B cells switch to IgA which is all secreted and not present in serum | |
| 3. |
Simulation of which of the following will lead to appearance of first antibody to appear following stimulation by an antigen? |
| A. | IgM |
| B. | IgA |
| C. | IgE |
| D. | IgG |
| Answer» B. IgA | |
| 4. |
The class of immunoglobulin, most abundant in body is |
| A. | IgD |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» D. IgM | |
| 5. |
Which is not a function of IgG? |
| A. | Major antibody in serum |
| B. | First antibody type produced against an antigen during the primary antibody response |
| C. | Activates or fixes complement |
| D. | Involved in opsonization |
| Answer» C. Activates or fixes complement | |
| 6. |
J chain is present in |
| A. | IgA |
| B. | IgM |
| C. | Both (a) and (b) |
| D. | IgE |
| Answer» D. IgE | |
| 7. |
Heat-labile class of immunoglobulins include |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» C. IgG | |
| 8. |
Which is the most efficient complement fixing class of antibody? |
| A. | IgE |
| B. | IgA |
| C. | IgM |
| D. | IgG |
| Answer» D. IgG | |
| 9. |
Which of the following (s) is/are function (s) of Fc fragment of IgG? |
| A. | It determines catabolic rate |
| B. | It binds complement |
| C. | It is related to passage of IgG across the placental barrier |
| D. | All of these |
| Answer» E. | |
| 10. |
Which of the following is the phylogenetically oldest immunoglobulin? |
| A. | IgE |
| B. | IgM |
| C. | IgG |
| D. | All are similar |
| Answer» C. IgG | |
| 11. |
The secretary component of sIgA is |
| A. | made by plasma cells that secrete dimeric IgA |
| B. | added to dimeric IgA by the M cell |
| C. | formed by cleavage of an epithelial cell receptor used to transport the dimeric IgA across the epithelial cell |
| D. | made by T cells |
| Answer» D. made by T cells | |
| 12. |
Anti-Rh antibodies are |
| A. | IgG type |
| B. | IgA type |
| C. | IgE type |
| D. | IgD type |
| Answer» B. IgA type | |
| 13. |
Which is not a function of IgA? |
| A. | Protect mucosal surfaces |
| B. | Fix complement |
| C. | Protect eyes |
| D. | Agglutinate antigen |
| Answer» C. Protect eyes | |
| 14. |
Which of the following theory of antibody production is most widely accepted? |
| A. | Side chain theory |
| B. | Clonal selection theory |
| C. | Direct template theory |
| D. | Indirect template theory |
| Answer» C. Direct template theory | |
| 15. |
Which of the following mediates Type I hypersensitivity reaction? |
| A. | IgE |
| B. | IgG |
| C. | IgM |
| D. | IgD |
| Answer» B. IgG | |