Which of the following statements is true regarding fat embolism -

• A. Most patients with major trauma involving long bones have urinary fat globules
• B. All patients with urinary fat globules develop fat embolism
• C. Peak incidence of respiratory insufficiency for pulmonary fat embolism is around day 7 after injury
• D. Heparin as an anticoagulant decreases mortality and morbidity in fat embolism syndrome