Regarding familial breast cancer, which of the following statements is

1.	Regarding familial breast cancer, which of the following statements is true?
A.	The majority of cases are also associated with mutations of the p53 gene.
B.	mutation of the BRCA1 gene may be associated with an increased risk of both breast and ovarian cancer.
C.	chemoprevention with tamoxifen is of proven benefit.
D.	most affected families share the same specific mutation of the BRCA1 gene.
E.	about 75% of affected family members develop breast cancer before the age of 35 years
Answer» C. chemoprevention with tamoxifen is of proven benefit.

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Regarding familial breast cancer, which of the following statements is true?

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