1.

Bisphosphoglycerate (BPG) cannot bind to the oxygenated R state of hemoglobin because

A. it is displaced from the heme by movement of the proximal histidine
B. it is displaced from the heme by oxygen
C. BPG binds to the R state with the same affinity as the T state
D. its binding pocket becomes too small to accommodate BPG
Answer» E.


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